COClNCO
COClNCO, also known as carbonyl chloride isocyanate, is a chemical compound with the formula COClNCO. It is a colorless liquid that is highly reactive and toxic. The compound is a derivative of carbon monoxide, chlorine, and isocyanate, and is used primarily as a reagent in organic synthesis. COClNCO is known for its ability to react with various nucleophiles, such as amines and alcohols, to form substituted ureas and carbamates, respectively. The compound is also used in the synthesis of pharmaceuticals and agrochemicals. However, due to its high reactivity and toxicity, COClNCO must be handled with extreme care. It is classified as a hazardous substance and should be stored and disposed of according to local regulations. The compound is typically prepared by the reaction of phosgene (COCl2) with an isocyanate source, such as an alkyl or aryl isocyanate. The reaction is usually carried out in the presence of a solvent, such as dichloromethane or tetrahydrofuran, to facilitate the reaction and improve the yield. COClNCO is a valuable reagent in organic synthesis, but its use requires careful consideration of safety and environmental factors.