CFTRi
CFTRi is an experimental chemical compound developed as a potential modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a chloride channel protein primarily expressed in epithelial cells, and its dysfunction is the primary cause of cystic fibrosis (CF), a hereditary genetic disorder characterized by thick mucus production leading to respiratory and digestive issues.
The development of CFTRi aims to restore or improve the function of defective CFTR channels in individuals
Preclinical studies of CFTRi have demonstrated its ability to enhance chloride transport in cell models expressing
Research into CFTR modulators like CFTRi is ongoing, and the goal is to provide more effective treatments