CF3COO

CF3COO, also known as trifluoroacetate, is a chemical compound with the formula CF3COO-. It is a derivative of acetic acid, where one hydrogen atom is replaced by a trifluoromethyl group. This compound is notable for its strong electron-withdrawing properties due to the presence of three fluorine atoms, which are highly electronegative.

Trifluoroacetate is commonly used in organic synthesis as a reagent. Its strong electron-withdrawing nature makes it useful in various chemical reactions, including the synthesis of pharmaceuticals and other organic compounds. It can also be used as a ligand in coordination chemistry, forming complexes with various metal ions.

In biological contexts, trifluoroacetate is of interest due to its potential as a metabolic inhibitor. It can inhibit the activity of enzymes involved in fatty acid metabolism, making it a useful tool in studies of lipid metabolism and related diseases.

Trifluoroacetate can be prepared through the reaction of trifluoroacetic acid with a suitable base. It is typically isolated as its sodium or potassium salt, which are more stable and easier to handle. These salts are soluble in water and organic solvents, making them versatile reagents in chemical synthesis.