Boranates

Boronate refers to a class of organoboron compounds characterized by a boron atom bonded to at least one carbon atom and often to oxygen atoms. The general structure can be represented as R B(OR')2 or similar variations, where R is an organic group and OR' represents alkoxy groups. These compounds are important intermediates in organic synthesis, particularly in carbon-carbon bond formation reactions. The Suzuki-Miyaura coupling is a prominent example where boronates, specifically boronic acids and their esters, react with organic halides or pseudohalides in the presence of a palladium catalyst to form new carbon-carbon bonds. This reaction is highly versatile and has found widespread application in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Boronates are typically stable and can be stored under ambient conditions, making them convenient reagents. Their synthesis often involves the reaction of organometallic reagents, such as Grignard reagents or organolithium compounds, with boron esters. Alternatively, transition-metal catalyzed borylation of organic compounds can also yield boronate products. The reactivity of boronates can be tuned by modifying the organic substituents, influencing their participation in various chemical transformations.