Biszfoszfonát

Biszfoszfonát is a class of drugs used to treat bone diseases. These medications work by slowing down the breakdown of bone tissue, which helps to increase bone density and reduce the risk of fractures. They are particularly effective in treating osteoporosis, a condition characterized by weakened and brittle bones. Biszfoszfonát can also be used to manage Paget's disease of bone and bone metastases, which are cancer that has spread to the bones. The mechanism of action involves inhibiting osteoclasts, the cells responsible for bone resorption. These drugs are typically administered orally or intravenously, with the frequency of administration varying depending on the specific biszfoszfonát and the condition being treated. Common biszfoszfonát medications include alendronate, risedronate, ibandronate, and zoledronic acid. While generally well-tolerated, potential side effects can include gastrointestinal issues, muscle and joint pain, and, rarely, more serious conditions such as osteonecrosis of the jaw and atypical femur fractures. It is important to discuss the risks and benefits of biszfoszfonát therapy with a healthcare professional.