Antibodydependent
Antibody-dependent is an adjective used to describe immune processes that require antibodies to mediate their action, typically through the Fc region of the antibody engaging Fc receptors or activating the complement system. These processes depend on antibodies to recognize a target and to recruit other components of the immune response.
The main antibody-dependent mechanisms include antibody-dependent cellular processes such as ADCP and ADCC. In antibody-dependent cellular
Receptors and cells involved include Fc receptors (such as Fcγ receptors and Fcα receptors) distributed on various
In clinical and research settings, antibody-dependent mechanisms influence the efficacy of vaccines and therapeutic antibodies, inform