Antiangi

Antiangi is a term that can refer to compounds or processes that inhibit angiogenesis. Angiogenesis is the physiological process through which new blood vessels form from pre-existing ones. This process is essential for normal growth and development, as well as for wound healing. However, it also plays a crucial role in the growth and spread of tumors, as cancer cells require a blood supply to survive and proliferate. Therefore, antiangiogenic therapies aim to block the formation of new blood vessels that feed tumors, thereby starving them and preventing their growth and metastasis.

There are various types of antiangiogenic agents, including small molecules that target specific signaling pathways involved in angiogenesis, as well as antibodies that block key growth factors like vascular endothelial growth factor (VEGF). These therapies have been developed and are used in the treatment of several types of cancer, such as colorectal cancer, lung cancer, and kidney cancer. While antiangiogenic treatments can be effective, they also carry potential side effects, which can include high blood pressure, bleeding, and impaired wound healing, as they can interfere with normal physiological angiogenesis. Research continues to explore new and more targeted antiangiogenic strategies to improve efficacy and reduce adverse effects.