AP2ERF
AP2ERF stands for APETALA2/Ethylene Responsive Factor, a large family of plant transcription factors within the AP2/ERF superfamily. Members are defined by the AP2 DNA-binding domain, a roughly 60–70 amino acid region that enables interaction with specific promoter sequences. In this family, many proteins contain a single AP2 domain (the ERF and DREB subfamilies), while a smaller subset carries two AP2 domains (the AP2 subfamily).
Functionally, AP2ERF proteins regulate gene expression in response to ethylene signaling and a range of abiotic
Genomic distribution and evolution show that the AP2ERF family is widespread across land plants, with gene
Applications and research focus on AP2ERF genes include improving crop tolerance to environmental stresses through breeding
See also: APETALA2, Ethylene Responsive Factor, DREB, GCC box, AP2/ERF superfamily.