4isoxazolone

4-isoxazolone is a chemical compound and a heterocyclic compound that contains a five-membered ring with two oxygen atoms and one nitrogen atom. The molecular structure of 4-isoxazolone consists of a planar, aromatic ring system with a nitrogen atom at the 1 position and an oxygen atom at the 4 position.

4-isoxazolone is known for its involvement in various chemical reactions and synthetic pathways. It serves as a precursor in the synthesis of other compounds, such as 3-amino-4-isoxazolone, which is used in pharmaceutical research. The compound's ability to form an imine functionality makes it an intermediate in biological reactions.

4-isoxazolone has been identified as a metabolite of certain pharmaceutical agents, such as fostamatinib, a spleen tyrosine kinase inhibitor used to treat autoimmune disorders. It has also been found to be involved in the metabolism of other compounds, including anti-cancer drugs.

In terms of its chemical properties, 4-isoxazolone is a polar, water-soluble compound that is stable over a wide range of pH values. It exhibits moderate reactivity towards electrophilic reagents, making it suitable for various chemical transformations. The compound's solubility and stability make it a useful intermediate in organic synthesis.

Research on 4-isoxazolone is ongoing, and the compound has been identified as a potential target for the development of new therapeutic agents. Its unique molecular structure and reactivity make it a valuable intermediate in pharmaceutical synthesis and a subject of interest in drug discovery research.