3q223

3q223 refers to a specific chromosomal region. The "3" indicates the third chromosome. The "q" denotes the long arm of the chromosome, as opposed to the "p" arm which is short. The "223" represents a specific band and sub-band designation on that arm, according to the International System for Chromosome Nomenclature (ISCN). Band 22 on the q arm is further subdivided into regions 2 and 3, hence 3q223.

Variations or abnormalities within the 3q223 region can be associated with certain genetic disorders. These can manifest in various ways depending on the precise nature of the alteration, such as deletions, duplications, or translocations. Research in cytogenetics and molecular genetics aims to identify the specific genes located within this region and understand their role in health and disease. Studies have linked variations in 3q223 to developmental delays, intellectual disability, and sometimes specific facial features. Further investigation is often required to determine the clinical significance of a particular anomaly in this chromosomal band.