3Formylthiophene

3-Formylthiophene, also known as thiophene-3-carbaldehyde, is an organic compound with the chemical formula C5H4OS. It is a derivative of thiophene, a five-membered heterocyclic aromatic ring containing one sulfur atom, with an aldehyde group (-CHO) attached at the 3-position of the ring. At room temperature, 3-formylthiophene is typically a liquid, often described as yellowish or colorless, with a characteristic odor.

This compound is a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and materials science applications. The aldehyde group is reactive and can undergo a variety of chemical transformations, including oxidation, reduction, and nucleophilic addition reactions. The thiophene ring itself can also participate in electrophilic aromatic substitution reactions. 3-Formylthiophene can be synthesized through various methods, often involving the formylation of thiophene or its derivatives. Its spectroscopic properties, such as NMR and IR, are well-characterized and aid in its identification and purity assessment.