2p131

2p131 refers to a specific locus on the short arm of chromosome 2, designated as band 13.1. This designation is part of the standard cytogenetic nomenclature used to describe the banding patterns on chromosomes. The short arm of a chromosome is denoted by 'p', and the bands are numbered from the centromere outwards. Therefore, 2p13.1 signifies a particular region within the 2p13 band.

Genes located within this region can be associated with various biological functions and, in some cases, with genetic disorders. The specific genes and their functions within 2p13.1 are identified through detailed genetic mapping and sequencing studies. Researchers investigate this locus to understand gene expression, regulation, and their roles in cellular processes.

Alterations or mutations within the 2p13.1 region, such as deletions, duplications, or translocations, can lead to a range of phenotypic effects. These variations are often detected through chromosomal analysis techniques like karyotyping or comparative genomic hybridization. The precise clinical manifestations depend on which genes are affected and the nature of the alteration. Scientific literature may reference 2p13.1 in the context of specific genetic syndromes or developmental abnormalities where chromosomal abnormalities in this region have been observed. Further research is ongoing to fully characterize the genetic makeup and clinical significance of the 2p13.1 locus.

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