2Bromopyridine

2Bromopyridine is an organobromine compound with the chemical formula C5H4BrN. It is a derivative of pyridine, where a bromine atom is substituted at the second position of the pyridine ring. It typically appears as a colorless to pale yellow liquid with a characteristic odor. 2Bromopyridine is soluble in many organic solvents.

This compound is primarily used as a building block in organic synthesis. Its reactivity stems from the bromine atom, which can be readily displaced or involved in various coupling reactions, such as Suzuki, Sonogashira, and Heck couplings. These reactions allow for the introduction of diverse functional groups onto the pyridine ring, making 2bromopyridine a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It can also serve as a ligand in coordination chemistry.

The synthesis of 2bromopyridine can be achieved through several methods, including the bromination of pyridine under specific conditions or through Sandmeyer-type reactions from 2aminopyridine. Like many organobromine compounds, it should be handled with care due to its potential irritant properties.