vWFkonsentraatteja
vWFkonsentraatteja, also known as von Willebrand factor (vWF) concentrates, are therapeutic products used to treat bleeding disorders caused by a deficiency or dysfunction of vWF. vWF is a large, multimeric protein that plays a crucial role in primary hemostasis, the process that stops bleeding. It is produced by endothelial cells and megakaryocytes and is involved in platelet adhesion, aggregation, and the stabilization of the platelet plug.
vWF concentrates are derived from human plasma and are typically prepared by a combination of fractionation
vWF concentrates are indicated for the treatment of bleeding episodes in patients with von Willebrand disease
The efficacy and safety of vWF concentrates have been well-established through clinical studies and real-world experience.