twoprotein
Twoprotein is a term used to describe a functional pair of proteins that operate together as a unit to perform a biological task. The concept emphasizes two distinct polypeptides that form a stable complex and achieve activity that neither subunit can accomplish alone. In many contexts, twoprotein refers to obligate dimers or heteromeric protein complexes in which the two subunits contribute complementary functions or structural features.
Characteristics of twoproteins include physical association of two polypeptides, interdependent stability and activity, and regulated assembly
Biological roles of twoproteins span signaling, transcriptional regulation, enzymatic activity, and molecular transport. Examples include transcription
Discovery and study: Twoprotein interactions are investigated with techniques such as yeast two-hybrid screening, co-immunoprecipitation, cross-linking,
See also: protein–protein interaction, dimer, heterodimer, protein complex.