tulopulsin

Tulipulsin is a protein found in the seeds of the tulip plant (Tulipa spp.). It belongs to a class of proteins known as lectins, which are characterized by their ability to bind to carbohydrates. Tulipulsin is specifically classified as a type II ribosome-inactivating protein (RIP). This means it has the ability to inhibit protein synthesis in cells by cleaving ribosomal RNA.

The primary function of tulipulsin within the tulip plant is thought to be related to defense. Lectins can act as a deterrent against herbivores and pathogens by interfering with their digestive or cellular processes. Tulipulsin's cytotoxic and enzymatic activity makes it a potent tool for the plant's protection. Research has explored its potential applications, including its cytotoxic properties for cancer research and its use in diagnostic assays due to its carbohydrate-binding specificity. However, its presence also means that raw tulip bulbs can be toxic if ingested by humans or animals, potentially causing gastrointestinal upset. The exact distribution and concentration of tulipulsin can vary among different tulip species and even within different parts of the same plant.