tsüklofosporiin

Tsüklofosforiin is a medication used to suppress the immune system. It belongs to a class of drugs known as alkylating agents, which work by interfering with the growth of certain cells in the body, particularly rapidly dividing ones like immune cells. Its primary use is in preventing organ rejection after transplantation. It is also employed in treating various autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis, where the immune system mistakenly attacks the body's own tissues.

The mechanism of action involves the drug being converted in the body into active compounds that damage DNA. This damage prevents immune cells, specifically T-cells and B-cells, from multiplying and functioning effectively. By reducing the activity of these immune cells, tsüklofosforiin can help to control the autoimmune response or prevent the rejection of a transplanted organ.

Tsüklofosforiin can be administered orally or intravenously. Like many potent medications, it can have significant side effects. These may include increased risk of infection due to immune suppression, bone marrow suppression leading to low blood cell counts, hair loss, nausea, and potential long-term effects on fertility and bladder function. Close medical supervision is essential during treatment to monitor for efficacy and manage adverse effects.