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tirucallanetype

Tirucallanetype is a term that appears in some chemical and natural product literature as a descriptor for compounds that share a tirucallane-type triterpenoid skeleton. The single-word form is not widely standardized; most scholarly writing uses tirucallane-type or tirucallane-type triterpenoids to denote this class.

Definition and structure: Tirucallane-type triterpenoids are C30 tetracyclic terpenoids based on the tirucallane skeleton, a specific

Usage and terminology: The exact concatenated form “tirucallanetype” is not standard; most sources use “tirucallane-type” or

arrangement
of
four
rings
derived
from
the
cyclization
of
squalene.
Compounds
in
this
class
exhibit
variations
in
functional
groups
and
degrees
of
unsaturation
at
various
positions,
and
they
are
typically
isolated
from
plants
as
secondary
metabolites.
The
term
is
used
to
categorize
these
compounds
in
discussions
of
their
biosynthesis,
isolation,
and
biological
activity.
Reported
biological
activities
in
some
studies
include
cytotoxic,
anti-inflammatory,
or
antimicrobial
effects,
depending
on
the
specific
substituents.
“tirucallane-type
triterpenoids.”
When
encountered
in
databases
or
early-stage
drafts,
the
intended
meaning
generally
refers
to
compounds
that
share
the
tirucallane
skeleton
rather
than
implying
a
formal,
universally
recognized
taxonomic
category.
See
also
tirucallane;
tirucallane-type
triterpenoids;
triterpenoids.