tilasemadine

Tilasemadine is a medication used to treat the symptoms of irritable bowel syndrome (IBS) with constipation. It belongs to the class of drugs known as antispasmodics, which work by relaxing the muscles in the intestines. Tilasemadine is available in tablet form and is typically taken orally.

The primary use of tilasemadine is to alleviate abdominal pain and discomfort associated with IBS. It is often prescribed as an alternative to other medications when patients do not respond well to them. Tilasemadine is generally well-tolerated, but like any medication, it can have side effects. Common side effects include nausea, constipation, and dizziness. More serious side effects are rare but can include severe allergic reactions and liver problems.

Tilasemadine should be used with caution in patients with certain medical conditions, such as liver or kidney disease, as well as in those who are taking other medications that can interact with it. It is important for patients to follow their healthcare provider's instructions regarding dosage and duration of use.

Tilasemadine was first approved for medical use in the United States in 1998. It is marketed under the brand name Tigan and is produced by various pharmaceutical companies. The drug's mechanism of action involves inhibiting the release of neurotransmitters in the gut, which helps to reduce muscle spasms and improve bowel function.