thiollinked
Thiol-linked refers to a chemical linkage where a thiol group (a sulfur atom bonded to a hydrogen atom, represented as -SH) is covalently attached to another molecule. This linkage is a common and important feature in many biological and chemical systems. In biological contexts, thiols are often found in cysteine residues of proteins. The formation of a disulfide bond (-S-S-) between two cysteine residues is a specific type of thiol linkage that plays a crucial role in stabilizing the three-dimensional structure of proteins. This linkage can be formed through oxidation of two thiol groups.
Beyond protein structure, thiol-linked molecules have applications in various fields. For instance, in drug delivery systems,