tertbutüül

tert-Butyl is a common organic functional group with the chemical formula -(C(CH3)3). It is derived from the alkane isobutane by removing one hydrogen atom from the tertiary carbon. This tertiary carbon is bonded to three methyl groups. The tert-butyl group is known for its steric bulk, meaning it occupies a significant amount of space. This steric hindrance can influence the reactivity and properties of molecules containing the tert-butyl group.

Due to its bulky nature, the tert-butyl group is often used as a protecting group in organic synthesis. It can be attached to alcohols, amines, and carboxylic acids to prevent them from reacting during certain chemical transformations. The tert-butyl protecting group can then be removed under acidic conditions. In addition, the tert-butyl group is a constituent of many pharmaceuticals and agrochemicals, contributing to their biological activity and physical properties. Examples include tert-butyl acetate and tert-butyl methyl ether, both used as solvents. The tert-butyl cation is a stable carbocation due to hyperconjugation from the methyl groups.