silybinin

Silybinin is the major active diastereomer of silybin, which is a complex of flavonolignans extracted from the seeds of the milk thistle plant, Silybum marianum. It is one of the primary constituents responsible for the plant's purported medicinal properties. Silybinin is characterized by its antioxidant and anti-inflammatory activities. Research has focused on its potential to protect the liver from various forms of damage, including that caused by toxins, viruses, and alcohol. This protective effect is thought to be due to its ability to scavenge free radicals and stabilize cell membranes. Furthermore, studies suggest that silybinin may inhibit the proliferation of certain cancer cells and promote apoptosis, or programmed cell death, in these cells. It is important to note that while research is ongoing, silybinin is often found in dietary supplements and herbal remedies rather than as a pharmaceutical drug. The bioavailability of silybinin can be a limiting factor in its therapeutic efficacy, and various formulation strategies are being explored to enhance its absorption. The chemical structure of silybinin is characterized by two phenylpropane units linked together.