sij1

Sij1 is a symbol that appears in some biological data sets and literature, but it does not correspond to a single, universally defined gene or protein across all species. The designation is not widely standardized, and its meaning is highly context dependent, often varying by organism and database. In practice, Sij1 may refer to different, poorly characterized or predicted entities in different genome annotations, or it may be a misreading or variant spelling of other similarly named genes.

In the context of yeast genetics, the closest and more established name is SIS1, which encodes a J-domain–containing co-chaperone that partners with Hsp70 in the protein folding and quality-control network. Because of historical naming variations, some references or older datasets may use Sij1 as a mistaken or alternate spelling for SIS1, but this is not a reliable or consistent identifier for yeast studies.

Across other organisms, there is no widely recognized, well-characterized gene or protein officially labeled Sij1. When Sij1 appears in a dataset for non-yeast species, it is often an uncharacterized predicted gene, a placeholder, or an annotation artifact rather than a defined biological entity.

For researchers seeking information on Sij1, the recommended approach is to search organism-specific resources (such as NCBI Gene, Ensembl, UniProt, SGD for yeast, or corresponding databases) using exact organism context and known synonyms, and to verify any functional claims against primary literature.