sidumiskonstandid
Sidumiskonstandid, also known as binding constants, are a fundamental concept in chemistry and biochemistry. They quantify the strength of a non-covalent interaction between two or more molecules or entities. This interaction can involve the binding of a small molecule to a larger biomolecule, such as a drug binding to a protein, or the association of two proteins.
The equilibrium constant, specifically the association constant (Ka) or dissociation constant (Kd), is used to express
These constants are crucial for understanding various biological processes. For instance, they are essential in determining
Experimental methods like surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), and fluorescence spectroscopy are commonly