sejtromok

Sejtromok is a term used in cell biology and pathology to describe remnants of cells after injury or death. Sejtromok include fragments of the plasma membrane, cytoplasm, and organelles such as mitochondria or lysosomes. They arise during necrosis, late-stage apoptosis, mechanical damage, or autophagic degradation when cellular components are broken down and released.

They are typically cleared by phagocytic cells—macrophages, neutrophils, and microglia in the nervous system. Efficient clearance is important to prevent prolonged inflammation; failure to remove sejtromok can contribute to ongoing inflammatory responses and may expose intracellular antigens that trigger adaptive immunity.

In histology and pathology, sejtromok appear as irregular, granular remnants in tissue sections or body fluids. Their abundance and localization can aid in assessing tissue injury, infection, or degeneration. Clinically, elevated or persistent sejtromok may indicate acute tissue damage, ischemia, trauma, or chronic inflammatory conditions.

Sejtromok are related to broader processes of cell turnover, including apoptosis, necrosis, autophagy, and phagocytosis. Understanding their formation and clearance helps explain certain histopathological patterns and inflammatory responses.