reseptorligand
Reseptorligand, or receptor ligand, is a molecule that binds to a receptor and modulates its activity. Binding typically induces a conformational change in the receptor, triggering intracellular signaling or altering function. Ligands can be endogenous, such as neurotransmitters and hormones, or exogenous, such as drugs, toxins, or experimental compounds.
Receptors are diverse: G protein–coupled receptors (GPCRs), ligand-gated ion channels, receptor tyrosine kinases, and intracellular/nuclear receptors.
Ligands are classified by their functional effect: agonists activate receptors; antagonists block receptor activation; inverse agonists
Pharmacological properties include affinity, potency, and efficacy, often summarized by Kd (binding affinity) and EC50 (effective
Understanding reseptorligander is central to pharmacology and drug discovery, guiding the design of selective ligands with