referensprov

Referensprov is a Swedish term commonly used in laboratory science, medicine and quality management to denote a reference sample or reference test that has known and documented properties. Such samples serve as benchmarks for calibrating instruments, validating analytical methods, establishing reference intervals, and conducting proficiency testing. The term can refer to certified reference materials, internal control specimens, or standardized test items depending on context.

Production and distribution of referensprov are typically handled by national metrology institutes, specialized producers, or accredited laboratories. Certified reference materials (CRMs) are characterized by traceable measurements and uncertainty statements, enabling comparability of results across laboratories and over time. In clinical laboratories, referensprov help define normal ranges and ensure assay accuracy; in environmental and industrial testing they support method validation and regulatory compliance.

Use of referensprov improves measurement traceability, repeatability and confidence in analytical results. Limitations include matrix mismatches between reference and real samples, limited availability for some analytes, degradation over time, and cost. Proper storage, handling and documentation are essential to maintain their value.

Related concepts include calibration standards, quality control samples and proficiency testing schemes. Together these tools form part of a laboratory’s quality assurance system, supporting reliable and comparable measurements across institutions and sectors.