rapamycina
Rapamycin, also known as sirolimus, is a macrolide compound produced by the bacterium Streptomyces hygroscopicus. It was discovered in 1972 in soil samples from Easter Island, whose indigenous name is Rapa Nui. Initially investigated for its antifungal properties, rapamycin was later found to possess potent immunosuppressive and antiproliferative effects.
The primary mechanism of action for rapamycin involves inhibiting the mammalian target of rapamycin (mTOR) signaling
Clinically, rapamycin and its analogs (rapalogs) are used to prevent organ transplant rejection. Its immunosuppressive properties
Beyond its established uses, rapamycin is a subject of extensive research for its potential therapeutic applications