pintaliitoskadheriinien
Pintaliitoskadheriinien, often referred to as cadherins, are a crucial family of cell adhesion molecules that play a vital role in multicellular organisms. These transmembrane proteins are responsible for calcium-dependent cell-cell adhesion, mediating homophilic interactions where cadherins of the same type on adjacent cells bind to each other. This binding is essential for maintaining tissue structure and integrity, as well as for facilitating cell sorting and segregation during embryonic development.
The cadherin superfamily is diverse, with numerous subtypes identified, each often exhibiting tissue-specific expression patterns. This
Dysregulation of cadherin function has been implicated in various pathological conditions, most notably in cancer. Loss