parabromobenzene

Parabromobenzene is an organobromine compound with the chemical formula C6H5Br. It is a substituted benzene ring where a bromine atom is attached to a carbon atom at the para position relative to another substituent, though in this case, the other substituent is implied to be hydrogen, making it bromobenzene. Specifically, it refers to bromobenzene, where the bromine atom is located at position 1 and the implicit hydrogen atoms are at positions 2, 3, 4, 5, and 6 of the benzene ring. This nomenclature is sometimes used to emphasize the position of the bromine in relation to other potential substituents, but when referring to the simplest brominated benzene, "bromobenzene" is generally sufficient.

Bromobenzene is a colorless liquid with a characteristic aromatic odor. It is a common reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Heck couplings. These reactions allow for the formation of new carbon-carbon bonds, making bromobenzene a valuable building block for creating more complex organic molecules, including pharmaceuticals, agrochemicals, and materials. It can also be used to prepare Grignard reagents and organolithium compounds, which are also important synthetic intermediates. Bromobenzene is sparingly soluble in water but soluble in common organic solvents like ethanol, ether, and benzene. It is considered a hazardous substance and should be handled with appropriate safety precautions.