pNitrophenyl
pNitrophenyl, commonly written as p-nitrophenyl, designates the para-nitro-substituted phenyl group, a benzene ring bearing a nitro substituent at the 4-position relative to the point of attachment to the rest of the molecule. The two substituents—nitro and the linking group—are arranged para to each other.
In organic synthesis, the p-nitrophenyl moiety is widely used as a leaving group. Its electron-withdrawing nitro
In biochemistry and enzymology, p-nitrophenyl derivatives are employed in colorimetric assays. Of particular importance is p-nitrophenyl
Preparation is typically by nitration of phenol derivatives to give the para isomer, or by introduction of