p65alayksiköt
p65 alayksiköt is a Finnish term referring to the p65 subunits of the NF-κB transcription factor family. In humans, these subunits are traditionally encoded by the RELA gene and form central components of active NF-κB dimers that regulate a wide range of immune and inflammatory genes. The phrase p65 alayksiköt is used in scientific literature to denote the functional entities derived from or containing the p65 subunit.
Structure and dimerization are key to the role of p65 subunits. The p65 protein contains a Rel
Activation and mechanism of action. In resting cells, NF-κB dimers, including those with p65, are held in
Regulation and post-translational modification. p65 activity is modulated by phosphorylation, acetylation, ubiquitination, and interactions with coactivators
Clinical significance. Abnormal p65 signaling is linked to inflammatory diseases, autoimmune conditions, and various cancers. Because