p49s

The term "p49s" can refer to several different entities, most commonly relating to proteins or genes. One significant instance is the protein P49, also known as KRT49. This protein is a type II keratin, a component of the cytoskeleton in epithelial cells. Keratins are intermediate filament proteins that provide structural support and are involved in cell adhesion and differentiation. KRT49 is primarily expressed in stratified epithelia. Mutations or altered expression of keratins, including KRT49, can be associated with various skin conditions and diseases.

Another context for "p49s" might appear in scientific literature referring to specific protein isoforms or post-translational modifications where a molecular weight of approximately 49 kilodaltons is observed. This could be a distinct protein or a modified version of a known protein. Without further context, pinpointing a single, universally recognized "p49s" entity beyond KRT49 is difficult, as it often depends on the specific research field or experiment. Researchers may use "p49s" as a shorthand for a protein of that approximate size that they are investigating.