oxacilín

Oxacillin is a narrow-spectrum antibiotic belonging to the penicillinase-resistant penicillin class. It is primarily used to treat infections caused by penicillinase-producing strains of Staphylococcus, particularly methicillin-susceptible Staphylococcus aureus (MSSA). Oxacillin works by inhibiting bacterial cell wall synthesis, leading to bacterial death.

It is administered intravenously or intramuscularly, and is often used for moderate to severe staphylococcal infections such as skin and soft tissue infections, bone and joint infections, pneumonia, and endocarditis. Due to its narrow spectrum, it is not effective against Gram-negative bacteria or methicillin-resistant Staphylococcus aureus (MRSA).

The most common side effects of oxacillin include gastrointestinal upset, allergic reactions (such as rash and itching), and injection site pain. More serious side effects can include liver dysfunction, kidney problems, and a reduction in blood cell counts. It is important to inform healthcare providers of any known allergies, especially to penicillins or cephalosporins, before oxacillin treatment. Dosage and duration of treatment are determined by the type and severity of the infection, as well as the patient's kidney function. Oxacillin is generally considered safe and effective when used appropriately under medical supervision.