orthophenetidine

orthophenetidine is an organic compound with the chemical formula C8H11NO2. It is a derivative of phenetidine, specifically an isomer where the ethoxy group is attached to the ortho position of the aniline ring. This compound is also known as 2-ethoxyaniline.

orthophenetidine typically appears as a liquid or low-melting solid. Its synthesis often involves the ethylation of 2-aminophenol or the reduction of 2-ethoxynitrobenzene. It can be used as a chemical intermediate in the synthesis of various dyes, pharmaceuticals, and other organic compounds. Its reactivity is characteristic of aromatic amines, undergoing reactions such as diazotization and acylation.

In terms of applications, orthophenetidine has found use in the production of azo dyes, contributing to a range of colors. It has also been investigated for its potential in medicinal chemistry, although it is not a widely used pharmaceutical itself. Like many aromatic amines, orthophenetidine should be handled with care, as it can be toxic and may cause irritation. Information regarding its specific safety profile and handling precautions is available in chemical safety datasheets.