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Omalizumab is a medication used to treat certain types of asthma and chronic spontaneous urticaria. It is a monoclonal antibody, a type of biologic therapy that targets and neutralizes immunoglobulin E (IgE), a key player in allergic reactions. By reducing IgE levels, omalizumab helps to prevent the release of inflammatory chemicals that cause symptoms of asthma and urticaria.

For asthma, omalizumab is typically prescribed for individuals with moderate to severe allergic asthma that is not well-controlled by inhaled corticosteroids. It is administered via subcutaneous injection every two or four weeks, depending on the dosage. In chronic spontaneous urticaria, it is used for patients who continue to experience symptoms despite treatment with antihistamines. The administration schedule is similar for this indication.

The effectiveness of omalizumab is usually assessed by monitoring symptom improvement, such as a reduction in asthma exacerbations or urticaria flares, and a decrease in the need for rescue medications. Like all medications, omalizumab can have side effects. Common side effects include injection site reactions, headache, and fatigue. More serious, though rare, side effects can include anaphylaxis. Therefore, it is important for patients to be monitored by a healthcare professional during and after administration. Omalizumab is not a cure for these conditions but rather a management tool to improve quality of life.