nukleosomin
Nucleosomin is a protein that plays a crucial role in the structural organization of chromatin, the complex of DNA and protein found in the nucleus of eukaryotic cells. First identified in the slime mold *Physarum polycephalum*, nucleosomin has since been found in various organisms, including humans, where it is known as histone H2A, H2B, H3, and H4. These histones form the core of nucleosomes, the fundamental repeating units of chromatin.
Nucleosomes consist of approximately 147 base pairs of DNA wrapped around an octamer of histone proteins—two
The function of nucleosomin extends beyond simple DNA packaging. Histone modifications, including acetylation, methylation, phosphorylation, and
In addition to its role in chromatin structure, nucleosomin is involved in DNA replication, repair, and the
Research on nucleosomin continues to expand our understanding of epigenetic regulation, which governs how genetic information