neurosteroidbased
Neurosteroidbased refers to compounds derived from cholesterol that are synthesized within the nervous system itself. Unlike classical steroid hormones, which are produced by peripheral endocrine glands, neurosteroids are synthesized de novo in neurons and glial cells. These molecules play a crucial role in modulating neuronal function and plasticity.
Neurosteroids exert their effects by interacting with various receptors in the brain, including GABA-A receptors, NMDA
The synthesis and metabolism of neurosteroids are tightly regulated and can be influenced by physiological and