nButoxide

nbutoxide is a chemical compound with the molecular formula C4H9O-. It is an anion derived from n-butanol by the loss of a proton from the hydroxyl group. In organic chemistry, alkoxides are commonly used as bases and nucleophiles. The nbutoxide anion is a strong base and is often employed in reactions requiring deprotonation of relatively acidic protons. It is typically generated in situ by reacting n-butanol with a strong alkali metal, such as sodium or potassium, or by reacting n-butanol with a metal hydride like sodium hydride. When used as a nucleophile, the oxygen atom of the nbutoxide anion attacks electrophilic centers. Common applications include its use in Williamson ether synthesis, elimination reactions, and as a catalyst in certain polymerization processes. Due to its strong basicity, nbutoxide can also promote undesired side reactions if not handled carefully. It is typically handled in anhydrous conditions as it readily reacts with water.