mtDNArakenteen
mtDNArakenteen refers to the structural organization of mitochondrial DNA (mtDNA) within a cell, including genome topology, gene content, regulatory regions, and the protein components that package and replicate the genome. It emphasizes how DNA arrangement influences transcription, replication, and the dynamics of heteroplasmy and inheritance.
Most mtDNA is a compact circular genome in animals, about 16,000 to 17,000 base pairs, encoding 37
Replication and transcription are tightly linked to topology. Replication initiates at OH and proceeds asymmetrically, with
Applications include phylogenetics, forensic genetics, and studies of mitochondrial disease, aging, and metabolism. Methodologies emphasize sequencing