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mgmL

mgmL is a unit of concentration that denotes milligrams of solute per milliliter of solution. It is commonly written as mg/mL, a standard notation in chemistry, pharmacology, and biology. The numeric value in mg/mL is equivalent to the number of grams per liter (g/L), since 1 mg/mL equals 1 g/L. In weight/volume terms, 1 mg/mL also corresponds to 0.1% w/v, because 1 g per liter is 0.1 g per 100 mL.

To convert mg/mL to molarity (M), the molecular weight of the solute is required. The relationship is

mgmL is widely used for pharmaceutical formulations, laboratory reagents, and in vitro biological assays where precise

Measurement of mg/mL relies on accurate mass determination (using a balance) and precise volume measurement (using

M
=
(mg/mL)
×
1000
/
MW,
where
MW
is
in
g/mol.
For
example,
a
5
mg/mL
solution
of
a
compound
with
a
molecular
weight
of
300
g/mol
equals
5
×
1000
/
300
=
16.7
mM.
dosing
in
small
volumes
is
needed.
Solutions
in
culture
media,
intravenous
preparations,
and
topical
formulations
are
often
described
in
mg/mL.
It
is
important
to
recognize
that
mg/mL
expresses
mass
per
volume
and
is
not
inherently
a
molar
concentration;
comparing
across
substances
with
different
molecular
weights
requires
conversion
to
molarity
or
another
standard.
pipettes
or
volumetric
flasks).
Temperature
can
affect
solution
volume,
so
mg/mL
values
typically
assume
a
defined
temperature
range
(commonly
around
room
temperature).