metabolizována

Metabolizována is the past passive participle of the verb metabolizovat, meaning to be metabolized. In biological and chemical contexts, this refers to the process by which a substance, such as a drug, nutrient, or toxin, is chemically altered by an organism. This alteration typically occurs in the liver, although other organs can also be involved. Metabolism often transforms a substance into a more water-soluble form, facilitating its excretion from the body. This transformation can also activate or deactivate a substance, affecting its biological activity. For example, a drug might be metabolized into an active metabolite that exerts a therapeutic effect, or it might be metabolized into inactive byproducts that are then eliminated. The rate and pathways of metabolism can vary significantly between individuals due to genetic factors, age, diet, and the presence of other substances. Understanding how substances are metabolized is crucial in fields like pharmacology, toxicology, and nutrition for predicting drug efficacy and safety, assessing the impact of environmental toxins, and optimizing dietary intake.