matriisivaikutusten
Matriisivaikutukset, known in English as matrix effects, refer to the phenomenon where the signal response of an analyte in an analytical measurement is influenced by other components present in the sample matrix. This means that the concentration of the analyte is not directly proportional to the measured signal because the surrounding substances, the matrix, alter the ionization efficiency, extraction efficiency, or detector response.
Matrix effects can significantly impact the accuracy and precision of analytical results, particularly in complex samples
To mitigate matrix effects, various sample preparation techniques are employed. These include extraction methods like liquid-liquid
Another common approach to compensate for matrix effects is the use of internal standards. An internal standard