leukocytrörelse

Leukocyte movement, also known as leukokinesis or diapedesis, refers to the process by which white blood cells (leukocytes) migrate from the bloodstream to tissues. This crucial function is a vital part of the immune response, enabling leukocytes to reach sites of infection, inflammation, or injury. The movement typically involves several steps. First, leukocytes in the bloodstream slow down and adhere to the inner lining of blood vessels (endothelium) at the site of interest. This adhesion is mediated by specific adhesion molecules on both the leukocyte and the endothelial cells. Following adhesion, the leukocytes flatten and squeeze between the endothelial cells, a process called diapedesis or extravasation, to enter the surrounding tissue. Once in the tissue, leukocytes are guided by chemical signals, a process known as chemotaxis, towards the source of the signal. This directed movement allows them to effectively reach and address the specific area requiring immune intervention. The ability of leukocytes to move freely through tissues is essential for defending the body against pathogens and for tissue repair. Defects in leukocyte movement can lead to impaired immune function and increased susceptibility to infections.