Home

lemoglobina

Lemoglobina is not a standard term in biology, and it most likely refers to hemoglobin, the oxygen-carrying protein of red blood cells, in languages or contexts where the spelling differs slightly. In scientific use, the term most commonly encountered is hemoglobina or hemoglobina/hémoglobine depending on the language.

Hemoglobin is a tetramer composed of four protein subunits, typically two alpha and two beta chains in

In humans, there are several hemoglobin types, including HbA (adult), HbA2, and HbF (fetal). The proportion of

Synthesis occurs in bone marrow, and degradation takes place mainly in the spleen and liver, with iron

adults,
each
with
a
heme
prosthetic
group
containing
iron
in
the
ferrous
(Fe2+)
state.
Each
heme
can
reversibly
bind
one
molecule
of
oxygen,
enabling
the
protein
to
transport
oxygen
from
the
lungs
to
tissues
and
to
carry
carbon
dioxide
back
to
the
lungs
for
exhalation.
The
binding
of
oxygen
is
cooperative,
giving
a
sigmoidal
oxygen-hemoglobin
dissociation
curve
and
allowing
efficient
loading
in
the
lungs
and
unloading
in
tissues
where
it
is
needed.
these
variants
changes
with
development
and
health.
Abnormalities
in
hemoglobin
can
lead
to
disorders
such
as
sickle
cell
disease,
various
forms
of
thalassemia,
or
methemoglobinemia.
Hemoglobin
levels
are
a
standard
measure
in
blood
tests
and
reflect
aspects
of
red
blood
cell
mass
and
oxygen-carrying
capacity.
recycled
for
new
hemoglobin
synthesis.