lateralflödesbaserade

Lateralflödesbaserade, often translated as lateral flow-based, refers to a type of immunoassay that is designed to detect the presence of a specific substance in a sample through a visual, qualitative result. These assays are commonly found in rapid diagnostic tests, such as home pregnancy tests, COVID-19 antigen tests, and drug screening kits. The fundamental principle relies on capillary action to draw a liquid sample across a porous membrane. As the sample moves, it interacts with specific antibodies or antigens immobilized on the membrane. If the target substance is present in the sample, it will bind to these immobilized reagents, leading to a visible color change at a designated test line. A control line is also typically present to ensure the test has been performed correctly and the reagents are functioning. The "lateral flow" aspect describes the movement of the sample and its components across the membrane in a direction parallel to the surface. This method offers advantages in terms of speed, simplicity, and portability, making it suitable for point-of-care or at-home testing environments where laboratory equipment and trained personnel may not be available. The sensitivity and specificity of lateral flow-based assays can vary depending on the specific design and the target analyte.