kolesterolupptag
Kolesterolupptag, also known as cholesterol absorption, refers to the process by which the body absorbs cholesterol from the gastrointestinal tract into the bloodstream. This process primarily occurs in the small intestine, where dietary cholesterol and biliary cholesterol are incorporated into micelles, facilitating their uptake by enterocytes (intestinal cells).
In the enterocytes, cholesterol is transported across the cell membrane by specific transporter proteins, such as
The efficiency of cholesterol absorption varies among individuals and can be affected by multiple factors, including
Medications like ezetimibe target the cholesterol absorption process by inhibiting NPC1L1, thereby reducing intestinal cholesterol uptake
Overall, cholesterol absorption is a vital physiological process that contributes to the regulation of cholesterol levels,