karboxipeptidázokat

Karboxipeptidázokat are a group of enzymes that play a crucial role in protein digestion. They belong to the family of peptidases, specifically exopeptidases, meaning they cleave amino acids from the carboxyl terminus of a peptide chain. This process is essential for breaking down large proteins into smaller peptides and individual amino acids, which can then be absorbed by the body.

These enzymes are synthesized in the pancreas as inactive zymogens, such as procarboxypeptidase A and procarboxypeptidase B. Upon reaching the small intestine, they are activated by other proteases. Carboxypeptidase A primarily cleaves aromatic and aliphatic amino acids from the carboxyl end of peptides, while carboxypeptidase B is more specific for basic amino acids like arginine and lysine.

The activity of karboxipeptidázokat is vital for nutrient absorption and is regulated to prevent uncontrolled protein breakdown. They are involved in various physiological processes beyond digestion, including blood pressure regulation through their interaction with angiotensin and the processing of hormones. Deficiencies or overactivity of these enzymes can lead to various health conditions, highlighting their importance in maintaining metabolic balance. Their study provides insight into protein metabolism and has implications for therapeutic interventions.