kaasukromatografiamassspektrometria

Kaasukromatografiamassspektrometria (GC-MS) is an analytical technique that combines the separation capabilities of gas chromatography (GC) with the identification and quantification capabilities of mass spectrometry (MS). This powerful analytical tool is widely used in various fields, including environmental analysis, forensic science, pharmaceuticals, and food safety.

In GC-MS, a sample is first injected into a gas chromatograph, where it is vaporized and separated into its individual components based on their volatility and interaction with a stationary phase. The separated components are then transferred to the mass spectrometer, where they are ionized and fragmented. The resulting ions are detected and analyzed based on their mass-to-charge ratio (m/z), providing a unique "fingerprint" for each compound.

The primary advantages of GC-MS include its high sensitivity, selectivity, and the ability to provide both qualitative and quantitative information about a sample. It is particularly useful for the analysis of volatile and semi-volatile organic compounds. However, GC-MS has limitations, such as the requirement for sample volatility and the potential for matrix effects that can interfere with analysis.

GC-MS is a versatile and powerful analytical technique that has revolutionized the way scientists and researchers analyze complex mixtures. Its combination of separation and identification capabilities makes it an invaluable tool in various scientific disciplines.