ionideks
Ionideks is a term used in molecular biology and bioinformatics to describe a specific class of ion channel modulators that selectively target a subset of potassium and sodium channels in neuronal tissue. The name derives from the Greek word ions, reflecting its interaction with charged particles, and the suffix –deks, a convention used in the field to indicate a compound with a defined docking configuration. Ionideks molecules are synthesized via a modular approach that incorporates cyclic peptide scaffolds linked to lipophilic side chains, allowing selective insertion into the lipid bilayer of excitable cells.
Early studies in the 2010s demonstrated that ionideks can dramatically alter action potential propagation in vitro,